RS 25344 hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

RS 25344 盐酸盐是一种磷酸二酯酶 (PDE) 4 抑制剂。

RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor.

RS-25344 hydrochloride (0-10 μM) is a potent inhibitor of sperm PDE activity, with an effective concentration of 0.3 nM and reaching maximum inhibition in the range of 100 nM.

RS-25344 hydrochloride (5 mg/kg; i.p.; twice daily for 72 h) results in significant increases in stomach weights in wild type C57BL/6 mice. RS-25344 hydrochloride (1 mg/kg; i.p.; 30 min prior to food bolus) increases gastric retention in mice.

——

Angiogenesis

PDE

phosphodiesterase (PDE) 4

——

——

152815-28-6

411.8

C19H14ClN5O4

>98% (HPLC)

DMSO:80mg/ml(194.27mM; need ultrasonic)

O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O.[H]Cl

——

(-20℃)

With Ice Pack

≥ 2 years